Pandemic is set in the near future, where a virus of epic proportions has overtaken the planet. There are more infected than uninfected, and humanity is losing its grip on survival. Its only hope is finding a cure and keeping the infected contained. Lauren (Rachel Nichols) is a doctor, who, after the fall of New York, comes to Los Angeles to lead a team to hunt for and rescue uninfected survivors.
Lizzie, a young woman with amnesia, slowly comes to realize that she may be responsible for the horrific murder of her parents. After returning to the family home, Lizzie had terrifying flashbacks to her childhood, and comes face to face with the true horror of her past.